Original Article

P. Devereaux, M. Marcucci, T.W. Painter, D. Conen, V. Lomivorotov, D.I. Sessler, M.T. Chan, F.K. Borges, M.J. Martínez-Zapata, C.Y. Wang, D. Xavier, S.N. Ofori, M.K. Wang, S. Efremov, G. Landoni, Y.V. Kleinlugtenbelt, W. Szczeklik, D. Schmartz, A.X. Garg, T.G. Short, M. Wittmann, C.S. Meyhoff, M. Amir, D. Torres, A. Patel, E. Duceppe, K. Ruetzler, J.L. Parlow, V. Tandon, E. Fleischmann, C.A. Polanczyk, A. Lamy, S.V. Astrakov, M. Rao, W.K. Wu, K. Bhatt, M.d. Nadal, V.V. Likhvantsev, P. Paniagua, H.J. Aguado, R.P. Whitlock, M.H. McGillion, M. Prystajecky, J. Vincent, J. Eikelboom, I. Copland, K. Balasubramanian, A. Turan, S.I. Bangdiwala, D. Stillo, P.L. Gross, T. Cafaro, P. Alfonsi, P.S. Roshanov, E.P. Belley-Côté, J. Spence, T. Richards, T. VanHelder, W. McIntyre, G. Guyatt, S. Yusuf, and K. Leslie

N Engl J Med 2022;386:1986-1997