Original Article

R.P. Whitlock, E.P. Belley-Cote, D. Paparella, J.S. Healey, K. Brady, M. Sharma, W. Reents, P. Budera, A.J. Baddour, P. Fila, P. Devereaux, A. Bogachev-Prokophiev, A. Boening, K.H. Teoh, G.I. Tagarakis, M.S. Slaughter, A.G. Royse, S. McGuinness, M. Alings, P.P. Punjabi, C.D. Mazer, R.J. Folkeringa, A. Colli, Á. Avezum, J. Nakamya, K. Balasubramanian, J. Vincent, P. Voisine, A. Lamy, S. Yusuf, and S.J. Connolly

N Engl J Med 2021;384:2081-2091